School-enterprise integration is an effective way to improve the running level of higher vocational colleges and universities and stimulate the innovation vitality of enterprises. This paper takes the higher vocational hotel management profession as the research object, combines IPO model and intuitionistic fuzzy hierarchical analysis method (IFAHP) to realize the construction of schoolenterprise integration performance evaluation index system, and utilizes the fuzzy comprehensive evaluation method (FCE) to carry out specific application of this evaluation system. On this basis, the fuzzy set qualitative comparative analysis (fsQCA) was used to explore the specific path of schoolenterprise collaborative education in higher vocational colleges. The empirical study shows that the constructed evaluation system of school-enterprise integration has high reliability and operability, which is conducive to horizontal and vertical comparisons of higher vocational colleges and universities, and is also applicable to the authorities of higher vocational colleges and universities and the third-party evaluation organizations for the performance evaluation of school-enterprise integration. At the same time, it also indicates that the realization of high-performance schoolenterprise collaborative parenting programs in higher vocational hotel management majors cannot be achieved through a single variable, but rather through the form of conditional grouping to play a key role. There are five paths to improve the effectiveness of university-enterprise collaborative parenting in colleges and universities, and in the paths, the enterprise scale, the pre-project input and the project implementation process are the core conditions to improve the effectiveness of university-enterprise collaborative parenting in higher vocational colleges and universities, and the combination of changes of the three plays a decisive role in different condition grouping states.