Based on the material demand forecasting model using BP neural network and particle swarm algorithm, the study builds the material whole chain response efficiency calculation model under dynamic multi-objective optimization by comprehensively considering the demand level weights of the affected area, and adopts genetic algorithm to assist the model solution in finding the optimal and decision-making. Taking an earthquake as a case for example analysis, the model in this paper can give the Pareto frontier, and combined with the weight coefficients after the transformation of the model solving results are more scientific and feasible, the demand satisfaction rate of the original model and the transformed model are 73.43% and 74.28% respectively, and the demand satisfaction rate of the affected points is improved by 4.24%, and this paper introduces the material allocation model of the demand level weights to be able to obtain better response efficiency of the whole chain of materials, which can provide important theoretical and practical guidance for the whole chain distribution of materials.