This study aims to explore how Hunan higher vocational colleges and universities can build a new ecosystem of industry-education integration through linear programming optimization strategies under the guidance of the strategy of developing the country through science and technology. The article evaluates and analyzes the ecosystem of industry-teaching integration in Hunan higher vocational colleges under the strategy of developing the country through science and education using linear programming method, and proposes relevant optimization strategies using the dyadic model of linear programming. The main factors affecting the efficiency of industry-teaching integration are identified through multiple regression analysis, including industry-teaching resources, incentive mechanism and management system. According to the linear programming model for maximizing the efficiency of industry-teaching integration in higher vocational colleges and universities, it is calculated that the efficiency of industry-teaching integration is maximized when Hunan higher vocational colleges and universities invest 3.6 million yuan, 0.3 million yuan and 0.5 million yuan in the resource consumption of industry-teaching resources, incentive mechanism and management system respectively. And it is proposed to build a new ecology of industry-education integration from three aspects of platform construction, cooperation docking and parenting path, respectively.