The article evaluates and predicts the effectiveness of medical English teaching through stepwise regression analysis in multivariate analysis method. It constructs an analytical prediction model of medical English teaching evaluation based on multivariate regression analysis. After initially establishing the evaluation index system of medical English teaching, effective evaluation indexes are screened out through stepwise regression, an effective evaluation index system of medical English teaching is constructed, and multiple regression equations for the quality of medical English teaching (students’ performance in medical English) are established. The prediction model of medical English teaching quality is constructed by eliminating the influential factors and abnormal data that do not have significance through multiple linear regression analysis. Teaching quality prediction equations were constructed by choosing teaching content, teaching method, teaching organization, teaching expression, teaching attitude, and overall effect of teaching. Among them, teaching content and teaching expression were significant, and the final prediction model of medical English teaching quality was Y=0.1958+0.1142*teaching content+0.7232* teaching expression. The 79.26% of students’ medical English performance can be explained by the multivariate linear regression analysis model.
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