Accelerating the formation of new-quality productivity is a must for transforming the mode of economic growth and realizing high-quality development. Taking the new quality productivity as the research perspective, this study selects the panel data of 30 provincial-level administrative regions in China from 2013 to 2023 as the research object, combines the regression analysis method to empirically analyze the influence paths between high-performance computing, the new quality productivity, and the economic policy innovation, and explores the role mechanism of the new quality productivity through the mediation effect analysis. The results show that the regression coefficients of high-performance computing on new quality productivity and economic policy innovation, as well as on new quality productivity and economic policy innovation, are all greater than 0 (p < 0.01), i.e., high-performance computing accelerates the formation of new quality productivity and further promotes the development of economic policy innovation. In the economically developed eastern region, this path of action is significant at the 1% level, and its driving effect of HPC accelerating new quality productivity on economic policy innovation is stronger, compared to the central, western and northeastern regions, which are significant at the 5% level. The article's analysis advances the understanding of the drivers of new quality productivity development and the effects, mechanisms, and regional differences of high-performance computing-enabled new quality productivity and economic policy innovation.
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