Let and be graphs and be a positive number. An -irregular labeling of is an assignment of integers from up to to either vertices, edges, or both in such that each sum of labels in a subgraph isomorphic to are pairwise distinct. Moreover, a comb product of and is a construction of graph obtained by attaching several copies of to each vertices of . Meanwhile, an edge comb product of and is an alternate construction where the copies of is attached on edges of instead. In this paper, we investigate the vertex, edge, and total -irregular labeling of where both and is either a comb product or an edge comb product of graphs.