A non-empty -element subset of an -element set , and a partition of , are said to be orthogonal if every class of meets in exactly one element. A partition type is determined by the number of classes of each distinct size of the partition. The Johnson graph is the graph whose vertices are the -element subsets of , with two sets being adjacent if they intersect in elements. A partition of a given type is said to be a -label for an edge in if the sets and are orthogonal to the partition. A cycle in the graph is said to be -labeled if for every edge of , there exists a -label, and the -labels associated with distinct edges are distinct. Labeled Hamiltonian cycles are used to produce minimal generating sets for transformation semigroups. We identify a large class of partition types with a non-zero gap for which every Hamiltonian cycle in the graph can be -labeled, showing, for example, that this class includes all the partition types with at least one class of size larger than 3 or at least three classes of size 3.