A Langford-type -tuple difference set of order and defect is a set of -tuples such that for and . In this paper, we give necessary and sufficient conditions on and for the existence of a Langford-type -tuple difference set of order and defect when . In the case that , we provide sufficient conditions for the existence of a Langford-type -tuple difference set of order and defect when is at most about . Using these results, we obtain cyclic -cycle systems of the circulant graph for all with and satisfying certain conditions.