A graph is 2-stratified if its vertex set is partitioned into two classes (each of which is a stratum or a color class). We color the vertices in one color class red and the other color class blue. Let be a 2-stratified graph with one fixed blue vertex specified. We say that is rooted at . The -domination number of a graph is the minimum number of red vertices of in a red-blue coloring of the vertices of such that every blue vertex of belongs to a copy of rooted at . In this paper we investigate the -domination number of prisms when is a 2-stratified 4-cycle rooted at a blue vertex.