We call the graph an edge -coloured if its edges are coloured with colours. A path (or a cycle) is called monochromatic if all its edges are coloured alike. A subset is independent by monochromatic paths if for every pair of different vertices from there is no monochromatic path between them. In it was defined the Fibonacci number of a graph to be the number of all independent sets of ; recall that is independent if no two of its vertices are adjacent. In this paper we define the concept of a monochromatic Fibonacci number of a graph which gives the total number of monochromatic independent sets of . Moreover we give the number of all independent by monochromatic paths sets of generalized lexicographic product of graphs using the concept of a monochromatic Fibonacci polynomial of a graph. These results generalize the Fibonacci number of a graph and the Fibonacci polynomial of a graph.