Let and be the degree-diagonal matrix and distance matrix of , respectively. Define the multiplier as the degree distance matrix of . The degree distance of is defined as , where is the degree of vertex , and is the distance between and . Obviously, is also the sum of elements of the degree distance matrix of . A connected graph is a cactus if any two of its cycles have at most one common vertex. Let be the set of cacti of order and with cycles. In this paper, we give the sharp lower bound of the degree distance of cacti among , and characterize the corresponding extremal cactus.