Let be a finite, nonempty set of nonzero integers which contains no squares. We obtain conditions both necessary and sufficient for to have the following property: for infinitely many primes , is a set of quadratic nonresidues of . The conditions are expressed solely in terms of purely external (respectively, internal) combinatorial properties of the set II of all prime factors of odd multiplicity of the elements of . We also calculate by means of certain purely combinatorial parameters associated with the density of the set of all primes such that is a set of quadratic residues of and the density of the set of all primes such that is a set of quadratic nonresidues of .