The cyclic edge-connectivity of a cyclically separable graph , denoted by , is the minimum cardinality of all edge subsets such that is disconnected and at least two of its components contain cycles. Since , where , for any cyclically separable graph , a cyclically separable graph is said to be cyclically optimal if . The mixed Cayley graph is a kind of semi-regular graph. The cyclic edge-connectivity is a widely studied parameter, which can be used to measure the reliability of a network. Because previous work studied cyclically optimal mixed Cayley graphs with girth , this paper focuses on mixed Cayley graphs with girth and gives some sufficient and necessary conditions for these graphs to be cyclically optimal.