A -rainbow dominating function (2RDF) of a graph is a function from the vertex set to the set of all subsets of the set such that for any vertex with , the condition that there exists with is fulfilled, where is the open neighborhood of . A rainbow dominating function is said to be a rainbow restrained domination function if the induced subgraph of by the vertices with label has no isolated vertex. The weight of a rainbow restrained dominating function is the value . The minimum weight of a rainbow restrained dominating function of is called the rainbow restrained domination number of . In this paper, we initiate the study of the rainbow restrained domination number and we present some bounds for this parameter.