A paired-dominating set of a graph is a dominating set of vertices whose induced subgraph has a perfect matching. The paired-domination number is the minimum cardinality of a paired-dominating set of . In this paper, we investigate the paired-domination number in claw-free graphs with minimum degree at least four. We show that a connected claw-free graph with minimum degree at least four has paired-domination number at most its order.