A dependence system on a set is defined by an operator , a function on the power set of which is extensive ( is included in ) and monotone (if is included in , then is included in ). In this paper, the structure of the set of all dependence systems on a given set is studied. The partially ordered set of operators ( if for every set , is included in ) is a bounded, complete, completely distributive, atomic, and dual atomic lattice with an involution. It is shown that every operator is a join of transitive operators (usually called closure operators, operators which are idempotent ). The study of the class of transitive operators that join-generate all operators makes it possible to express (the cardinality of the set of all operators on a set with elements) by the Dedekind number . The formula has interesting consequences for dependence system theory.