Let be an integer and let be a graph of order . A set of vertices of is an -dominating set (total -dominating) set of if every vertex of (, respectively) is within distance from some vertex of other than itself. The minimum cardinality among all -dominating sets (respectively, total -dominating sets) of is called the -domination number (respectively, total -domination number) and is denoted by (respectively, ). A set of vertices of is -independent if the distance (in ) between every pair of distinct vertices of is at least . The minimum cardinality among all maximal -independent sets of is called the -independence number of and is denoted by . Suppose is an -independent set of vertices of for which there exists a vertex of that is within distance from every vertex of . Then a connected subgraph of minimum size that contains the vertices of is called an -generalized in . It is shown that if contains no -generalized , then . Further, it is shown if contains no -generalized , , then . It is shown that if is a connected graph with at least vertices, then there exists a minimum -dominating set of such that for each , there exists a vertex at distance from and distance at least from every vertex of . Using this result, it is shown if is a connected graph on vertices, then and that . Finally, it is shown that if is a tree on vertices, then .