Let be a graph and be the complement of . The complementary prism of , denoted , is the graph formed from the disjoint union of and by adding the edges of a perfect matching between the corresponding vertices of and . A set is a locating-dominating set of if for every , its neighborhood is nonempty and distinct from for all where . The locating-domination number of is the minimum cardinality of a locating-dominating set of . In this paper, we study locating-domination of complementary prisms. We determine the locating-domination number of for specific graphs and characterize the complementary prisms with small locating-domination numbers. We also present upper and lower bounds on the locating-domination numbers of complementary prisms, and we show that all values between these bounds are achievable.