Much research has been done on the edge decomposition of copies of the complete graph with respect to some specified subgraph of . This is equivalent to the investigation of -designs of index . In this paper, we present a fundamental theorem on the decomposition of copies of a complete bipartite graph. As an application of this result, we show that necessary conditions are sufficient for the decomposition of copies of a complete bipartite graph into several multi-subgraphs with a number of vertices less than or equal to and the number of edges less than or equal to , with some exceptions where decompositions do not exist. These decomposition problems are interesting to study as various decompositions do not exist even when necessary conditions are satisfied.