Placing degree constraints on the vertices of a path yields the definitions of uphill and downhill paths. Specifically, we say that a path is a downhill path if for every , , . Conversely, a path is an uphill path if for every , , . The downhill domination number of a graph is defined to be the minimum cardinality of a set of vertices such that every vertex in lies on a downhill path from some vertex in . The uphill domination number is defined as expected. We explore the properties of these invariants and their relationships with other invariants. We also determine a Vizing-like result for the downhill (respectively, uphill) domination numbers of Cartesian products.